Answer: Neither, it should be performed by a qualified Software Tester andwitnessed by a Software Quality Engineer, a Systems Engineer, andthe customer/user representative. The Software Developer should be entirely out of the picture atthis point and only be responsible for fixing bugs found duringvalidation.
Answer: CPT codes are specifically related to billing and were setup by the AMA. ICD-9 are diagnostic codes and are more for documentation and so that other practitioners know exactly what disease you are talking about. They were setup initially by the WHO.
Answer: ASCII, the American Standard Code for Information Interchange, is the most commonly used way to represent character and numerical information in a seven-bit binary format, for values from 0 to 127. Most modern computer systems tend to use ASCII values of 128 and above for extended character sets.
EBCDIC, the Extended Binary Coded Decimal Interface Code, is an eight-bit binary format used by various IBM mainframe operating systems.
Answer: Code 19 is telling you that the computer has received the correct pulse width from your crankshaft sensor. Either your crankshaft sensor is dirty ( the sensor opperates by magnetics, and has a magnet in the tip. this magnet will over time accumulate metal particles from your engine) or has malfunctioned. The crankshaft sensor is located on the back of the engine block, just behind the starter.
Answer: A check digit, typically the last digit of a number, can be computed from the other digits. For example, if you have an account number 1234, the bank might add a 5th digit of 0 because 1+2+3+4=10 and the low digit of 10 is zero. So they would tell you your account number is 12340. Then if you type it in by mistake as 12350 or 12347 or some such, a web page could immediately know it was wrong before looking it up in the database.If you typed in 33310 by mistake, it would think the check digit was correct -- so you can see it is good for saying what is probably wrong, but not what is RIGHT. Real check digits will detect swapping of two digits (which the sum above does not). Also, today a check digit is less important than it was in 1980 as it is quick to actually look it up and see if it is a valid account number without using a check digit at all.
Answer: USP definition:"Validation of an analytical method is the process that establishes, by laboratory studies, that the performance characteristics of the method meet the requirements for the intended analytical applications."
Answer: Yes, in order to take into account unusual circumstances. For example you cannot properly value SunTrust Bank unless you take into account that they hold a very large share in Coke they bought for a few cents a share 100 years ago. That adjustment could be called a wildcard.
Answer: Verification is the checking process of any form of field that it is blank(empty) or not. mean in verification, fields of any form should not blank or empty.
Validation is the checking process of any form of field that the value of the field is correct according to that field like that name field has collect only char value, phone no field has collect only numeric value and so on........
Answer: The previously recorded answer in inaccurate on several levels (see below for quotations of previous repsonse)
Linearity is the correlation of a regression line. Range is typically derived from linearity. Range implies that the method developed corresponds to the "range"between 80-120% (ideally) of the expected sample range (concentration, wt. etc). For content uniformity, range is expected to be 70-130% of the test concentration. These are guidelines governed by ICH Q2 R1 (International Conference for Hamonisation).
In terms of HPLC method development: LOQ is the smallest amount that will give a S/N ratio of 10 meaning this is the smallest amount you may give a numerical value with confidence. TYPICALLY, THE LOWER RANGE (AND USUALLY LINEARITY) IS LOQ.
LOD is the smallest value that will give an S/N ratio of 3, meaning you can say the specific compound is there qualitatively, but not quantitate the compound.
Previous: "The range is any value that lies between the limit of detection (LoD) and the limit of quantitation (LoQ). Where the LoD is the lowest concentration that can be accurately measured and the LoQ is the highest concentration that can be accurately measured.
Linearity describes the correlation to a regression line that has been fit to the data that. For some nice pictures to explain this see regression line at:"