Answer: 578 mi - about 9 hours 21 mins driving time. LaFayette, GAm USA to Largo, FL, USA 1. Head north on Lafayette Square toward E Villanow St 171 ft 2. Turn right at E Villanow St 4.4 mi 3. Turn left at GA-136 E/GA-151 N/S Old Alabama Hwy 1.4 mi 4. Turn right at GA-136 E 14.6 mi 5. Turn left at GA-136 E/Resaca Lafayette Rd NW 6.4 mi 6. Turn right to merge onto I-75 S 142 mi 7. Slight right at I-475 S (signs for I-475 S/Bypass to 1-75 South Valdosta) 15.8 mi 8. Merge onto I-75 S Entering Florida 354 mi 9. Slight right at I-275 S (signs for I-275 S/Tampa/St Petersburg) 28.8 mi 10. Take exit 31 to merge onto FL-688 W/Ulmerton Rd 9.1 mi 11. Turn right at Seminole Blvd 1.0 mi 12. Turn right at 8th Ave SE 98 ft Largo, FLU, S
Go across to I-275. Follow signs to I-275 NORTH to TAMPA.
Take I-275 NORTH to I-75 NORTH.
Take I-75 NORTH to Knoxville, via I-475 NORTH (EXIT 156 off I-75 in GEORGIA) to bypass MACON, and via I-285 WEST BYPASS (EXIT 238B off I-75 in GEORGIA to get ono I-285 WEST BYPASS ; EXIT 20 off I-285 to get back onto I-75, follow signs to I-75 NORTH to CHATTANOOGA) to bypass ATLANTA.