Answer: Depends...If you take I-20, to I-35, to College Station, it will be about 318 miles.However, if you take I-20 to Tx-36, that shoots you straight through to College Station with a grand total of 270 miles. However, this rout take about an hour longer than going down 20 to 35. Trust me... the 2nd route is more scenic.
Answer: It is almost 6 and a half hours, going up south of Dallas and taking 20 over to Abilene. You can take other smaller roads, but it just adds time to the trip. It is 361 miles according to Google Maps.