Similar Questions

What chromosome does prader-willi syndrome affect?

  • Chromosome 15.

Add Comment & Answer


Name: *



Answers and Comments

  • Answer: It was named after the two doctors who diagnosed it
  • Answer: It is a disease of excessive eating and there is some link of some abnormal mind development.
  • Answer: A genetic disorder resulted in seven missing or unexpressed genes on chromosome 15
  • Answer: 1 in 15,000 people have it
  • Answer: Not in the scientific sence as the genes are not located on the sex chromosomes.It can rarley be caused by genes from the father mutating as the equivolent genes from the mother are almost silent due to gene imprinting. So in a more general sence it may be associated with the gender of the parent from whom deleted gene copys were recieved.
  • Answer: PWS is usually not inherited in MOSt cases. It occur as random events and is caused by the deletion of chromosome 15.
  • Answer: No cure yet. Therapies to improve muscle tone and feeding techniques to improve weight gain. Strict control of food intake to prevent obesity (growth hormone therapy improves muscle tone). Special education.
  • Answer: As of right now, there is no known cure for Prader-Willi Syndrome.
  • Answer: Generally speaking, Prader-Willi Syndrome is not inherited. It is a random error/mutation to the 15th chromosome that occurs at conception. In around 70% of the cases, the mutation is a deletion (or microdeletion) of some of the genes on the 15th chromosome. In around 25% of the cases the error/mutation occurs because the baby gets 2 15th chromosomes from the mom instead of one from mom and one from dad, and since the genes that impact the symptoms of PWS should come from the dad if the child has 2 sets from the mom the genes are silent and therefore it is the same as though they were missing/deleted. In the rarest of cases PWS is caused by an imprinting error which can either occur randomly at conception or be passed from the father (who would not have PWS himself)....again this last kind is extremely rare.

    See Sources and Related Links for the Prader-Willi Syndrome Association (USA) and more detailed information.
  • Answer: speech delay,poor physical coordination,hyperphagia,excessive weight gain,sleep disorders,scoliosis
  • Answer: It was discovered in 1863 by a Swiss Doctor named Labhart
  • Answer: it is believed that every 1 in 15,000 live births result in a child with prader-willi syndrome
  • Answer: Prader-willi syndrome occurs due to genetic mutation, it is believed that parents with a genetic abnormality, uneffected by the syndrome, pass the mutation to their children. Some studies suggest that the syndrome is due to missing genes in the paternal chromosome, but it may be a combination of both parents.