Answer: The driving distance between Tallahassee, FL and Columbia, MO is approximately 925 miles. The driving time would be approximately 15 hours 45 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
Turn left out of Columbia College onto Rogers St. Take Rogers St to Rangeline St (first street that you will approach). Turn left onto Rangeline St.
Rangeline St becomes ROUTE 763; continue straight onto ROUTE 763 NORTH, then take ROUTE 763 NORTH straight up to U.S. 63 NORTH.
Take U.S. 63 NORTH to ROUTE EE to DOWNTOWN MOBERLY; EXIT, then turn left off the exit ramp onto ROUTE EE - WEST to DOWNTOWN MOBERLY.
Take ROUTE EE - WEST on Rollins St all the way across town to College Ave, which is where you cannot go any further. Turn right onto College Ave, then turn left at the stop sign onto W Reed St, then turn left into the community college parking lot.